VJ Instruments'

Digital Plethysmometer: Precise Edema Measurement and Inflammation Monitoring

The Plethysmometer is a highly valuable apparatus designed to accurately measure changes in small paw volume, particularly when assessing edema—an essential indicator of inflammation. This innovative device facilitates the precise quantification of micro-volume alterations caused by the displacement of water, primarily achieved through the insertion of a Rat or Mouse paw.

How Our Digital Plethysmometer Works: A Step-by-Step Guide

To better understand the operation of the VJ Instruments Plethysmometer, we offer a detailed video section demonstrating the setup and functionality of the apparatus. Watch our video to learn how this advanced technology can assist in measuring and analyzing paw swelling, which can be indicative of inflammation in research involving rats and mice.

The Plethysmometer by VJ Instruments serves as a valuable apparatus for the precise measurement of small paw volume changes, which can be indicative of inflammation. This innovative device is primarily designed for research involving rats and mice, where monitoring and quantifying paw swelling, or edema, is essential. Here’s how our Digital Plethysmometer can be applied effectively:

  • Inflammation Studies: Researchers can use the plethysmometer to study and monitor inflammation in animals. Paw volume changes can be a critical parameter for understanding the development, progression, and resolution of inflammatory responses.

  • Drug Efficacy Testing: Pharmaceutical and biotechnology companies can employ this technology to assess the effectiveness of anti-inflammatory drugs or novel therapeutic interventions by measuring changes in paw volume before and after treatment.

  • Pathological Research: The Digital Plethysmometer is a valuable tool for studying pathological conditions that affect paw volume, offering insights into disease progression, severity, and therapeutic responses.

  • Toxicology Studies: In toxicological research, the apparatus can be used to assess the impact of various substances on paw swelling, providing critical data for safety assessments.

  • Preclinical Trials: Prior to clinical trials in humans, preclinical research often involves animal models. The Digital Plethysmometer aids in monitoring physiological responses in rodents, ensuring the safety and efficacy of potential treatments.

  • Research Validation: Researchers can use this apparatus to validate their findings and hypotheses by accurately quantifying changes in paw volume due to various experimental conditions.

The Digital Plethysmometer is a versatile tool that significantly enhances the accuracy and efficiency of research involving animal models. Its advanced imaging technology, user-friendly interface, and high accuracy make it an indispensable instrument for scientists and researchers in a wide range of fields.

Features: Our Plethysmometer offers a range of features that set it apart from conventional plethysmometers:

  1. Simple User Interface: Our user-friendly interface makes it easy to operate the plethysmometer, ensuring that both novice and experienced researchers can use it effectively.

  2. Water Loss Correction: Each reading benefits from a water loss correction feature, ensuring the most accurate results for paw volume measurements.

  3. Image-Based Technology: The device utilizes state-of-the-art imaging technology, including a camera and specialized software, to directly calculate changes in paw volume.

  4. Foot Switch: A USB foot switch is included for easy and convenient operation.

  5. User-Friendly Computer Software: Our software is designed to provide precise measurements and is accessible to users with varying levels of technical expertise.

  6. Accuracy: The VJ Instruments Digital Plethysmometer boasts an impressive accuracy of 0.01 ml, ensuring dependable and consistent results.

  7. Tube Diameter Options: The device is available with a 35mm tube diameter for rats and mice, and an optional 25mm tube diameter can be chosen based on your research needs.

  8. No Need for Sensors: Unlike other plethysmometers, our digital plethysmometer eliminates the need for sensors, which can save on costs associated with sensor replacements.

Model No. VJDP-01
Material of Composition SS304, Acrylic & Glass
Resolution 0.01 ml
Cube 2cc, 1cc
Recommended PC Specification – Windows Version: Windows 11 (64-bit)
– Processor: Intel Core i7, 11th Generation
– RAM: 16GB
– Hard Drive: 1TB SSD
– Display: ≥ 20 inch, 1920 x 1080
– USB Ports: 2



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Frequently Asked Questions

We understand that you may have questions about our VJ Instruments Plethysmometer, its applications, and how it can benefit your specific needs. Here are some common questions and answers to provide you with quick and helpful information:

A Digital Plethysmometer is an apparatus designed to measure changes in small paw volume, which can indicate inflammation. It works by immersing a rat or mouse paw in a water-filled U-shaped glass cell. A camera and specialized software are used to directly calculate paw volume changes.

The VJ Instruments Digital Plethysmometer offers advanced features, including a simple user interface, water loss correction, image-based technology, a USB foot switch, user-friendly software, high accuracy (0.01 ml), and the option for different tube diameters (35mm for rats and mice, with a 25mm option). Importantly, it doesn’t require sensors, saving on replacement costs.

This apparatus is primarily used for studying inflammation, drug efficacy testing, pathological research, toxicology studies, preclinical trials, and research validation. It is essential for assessing paw volume changes in various experimental conditions.

  • We recommend Windows 11 (64-bit) with an Intel Core i7, 11th Generation processor, 16GB of RAM, a 1TB SSD, and a display with a resolution of at least 1920 x 1080 and a size of 20 inches or more. You need at least 2 available USB ports.

You can access research publications at this link for more information on its applications and capabilities.

Yes, we offer a detailed video guide in the “How It Works” section of our webpage, demonstrating the setup and operation of the Digital Plethysmometer for accurate paw volume measurements.

Yes, we offer training and support to ensure that users can effectively operate the Digital Plethysmometer and obtain accurate results.

The Digital Plethysmometer offers precise and efficient paw volume measurement, making it a valuable tool for researchers in a wide range of fields. It contributes to the understanding of inflammation, drug testing, disease modeling, and more, enhancing the quality and accuracy of research outcomes.

International Clients

Industrial Clients

IITs, AIIMS, CSIR, Government and Private Institutes

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